COMPARATIVE STUDY BETWEEN OXYTOCIN VERSUS TRANEXAMIC ACID AND ETHAMSYLATE COMBINATION IN REDUCING INTRAOPERATIVE BLOOD LOSS IN MYOMECTOMY

Background: Fibroids are the most common benign pelvic tumors affecting about 20% of women above 35 years age. The diverse symptomatology fibroids can be attributed to size, number and location tumors. symptoms include menorrhagia, infertility, abdominal mass pressure effects. Objective: To compare efficacy tranexamic acid ethamsylate versus IV oxytocin infusion in reducing blood loss during myomectomy. Patients Methods: This study involved ninety undergoing myomectomy for symptomatic uterine myoma divided randomly into three equal groups: Group A (Tranexamic group) received 1 g (2 ampoules kapron 500 mg) (1 ampoule dicynone) just before skin incision, B (Oxytocin 30 IU ml normal saline will administered myomectomy, C (Saline 110 incision. was conducted Sayed Galal Al-Azhar University Hospital El-Galaa Teaching period time from December 2018 2019. Results: Using dicynone resulted a significant reduction than using immediately start surgery (509.24±57.28 Tranexamic group vs. 720.13±112.62 group). Conclusion: more effective transfusion requirement with stable hematological hemodynamic profile.